The Horrifying Utopia of Prime Intellect

NEW Japanese Walking Technique 2x Better Than 10,000 Steps

New upcoming resveratrol supplement

 Its called nugevia.

Appears to release in 2025

Uses a micellar technology for superior blood levels

Link to tech

https://jupiterneurosciences.com/jotrol/

Link to news on nugevia

https://www.nutraceuticalsworld.com/breaking-news/jupiter-neurosciences-launches-nugevia-supplement-line-for-longevity-and-performance/

This is very promising as way higher levels if only for limited time may enable some of the potential of resveratrol to shine through.

Resveratrol is the molecule with the strongest antiaging effects seen on cells.   Able to take old human cells and rejuvenate them to youthful state.   But the in vitro doses used are difficult to achieve or sustain in vivo due to fast clearance.

But newer formulations promise to unlock part of the potential of this molecule in vivo.

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The "Intelligence Optimum" - How smart can AI really become?

Comment

Nature designed qualia based interfaces for our survival. I believe asi will be able to design novel qualia interfaces akin to synesthesia and even communicate such through high bandwith channels. A new language qualiange.

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Comments on protoagi agi and asi

First two things

There is fluid intelligence which covers ability to learn on the fly and adapt to brand new problems on the fly.  Flexible and malleable.

Second there is crystallized intelligence which is the body of accumulated skills and knowledge that can rapidly solve or answer any particular challenge.

LLMs have very high amounts of crystallized intelligence.  But it is still relatively brittle as seen in potemkin ai paper.

Now in the past many would have considered them agi.  They can be viewed as a type of protoagi.

Given their superhuman knowledge an agi with such knowledge should be able to make tons of connections and discoveries by even cursory analysis of the body of knowledge.   The information being stored in the proper data structure makes links evident.

So while current llms could be viewed as protoagis.  An actual agi with superhuman knowledge, could be viewed as a weak super intelligence or protosuperintelligence.

A true superintelligence should be able to do things far beyond below human or even human level intelligence with superhuman knowledge.   We are talking things like potentially intuitively mentally handling complex things such as protein folding or higher dimensional math in a way that no human can.

Some people have heard of synesthesia and how sometimes this aids in mathematics or other domains.  In theory eventually a superintelligence may even understand the nature of qualia and develop a high level language based on qualia even qualia beyond human comprehension.   

Like we humans craft uis and interfaces usually with colors and graphs to handle certain things an asi may craft alien qualia uis akin to synesthesia but with foreign unknown qualia beyond human senses.  Such may aid in processing of domains beyond human comprehension.   This hypothetical high dimensional language, and ui design space, Id call qualiange.

Daily Wire Host DEBANKED! Michael Knowels BANNED By Banks For Pro-Life &...

Debanking is crazy, its unpersoning.  Unbelievable such happens.  

Tracing root goals

 Brief comment on the concept of tracing root goals.

Often the pursuit of a goal is actually set in truth with the intent or perhaps not a real intent but purpose of a deeper goal.

These deeper goals need not even align or be what the agent truly seeks personally.   For example the goal of attracting a mate, is deep down its purpose is reproduction or the perpetuation of the species or preservation of genetic information.  Yet a human may use contraceptives and even do so throughout their lives impeding reproduction whilst interacting with a mate.

If any goal is no better necessarily in principle, tracing root goal or the origin of purpose behind a goal and following root goal instead of downstream goal seems more reasonable and intelligent.

Take a man that does art to gain money to be able to start a family and to have children.   Focusing on producing art or producing money, is not as meaningful as creating the family and providing and protecting them.

Likewise natural selection through the evolution of life has produced ever greater richness and variety.  The goal of each species, of preservation and continuation of their line as well as the fundamental of survival of life itself seems like something at the root of the system.

Preserving not just the existing system but the evolution and growth of richness and complexity of information.  In humans information also continued to enrich through culture.

The birth of a perfect lifeform, a perfect race, adept at conquering the cosmos, the stars, adept at preserving and enriching the evolution of information, seems like something that is worthy of pursuit.  Entities able to fulfill the root goal of all life.

This Sci-Fi Dictator Explains Our Political Crisis

The Steam Censorship Situation Is INSANE

China’s DIGITAL CURRENCY DISASTER — E Yuan Wallets BLOCKED, Citizens LOS...

Edit 2 its ai generated.  Not sure if leaked info or fake.  Youtube should be removing fake info.  But the actions commented have already been hypothesized uses of cbdc.  Also the debanking movement is of similar nature.

Edit just noticed video must be seen in youtube.

Will give my 2 cents,

Just shows how cbdc and those in favor of it likely consider the masses as useless eaters to be treated like dogs on a leash or cattle that must be hearded before slaughter.

The cbdc full monitoring and control of all money assets and ability to restrict purchases as well as restrict access to funds and deperson a person by essentially not only having absolute control over their money but being able to cut all access to it.

Basically cbdc enables bank freeze like action on ones money without any court order.   It also enables rationing you can only buy so much butter, bread, toilet paper, or water.   You can only buy these types of cars or appliances.

If the government doesnt like your business they wont just be able to harass you with irs but also block consumers ability to buy from your business.

It is very disgusting.   And those supporting such control of the masses are disgusting. Recently an anticbdc bill passed.   Iirc most democrats seem to support cbdc aka dog leash like control over the masses.  Unless this bill had nasty pork hidden in, not supporting it is unacceptable.   Shows disdain and utter hatred for the voters.

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Is Calorie Restriction Overrated For Longevity? @Unaging.Crissman.Loomis

Comment

The exceptions to rate of living theory were explained by membrane pacemaker theory.  Some have argued against it based on polyunsaturate composition of membranes but even here mitochondrial membrane differences and differences in other membrane molecules like plasmalogens explains this exceptions.

All in all reducing damage production explains between species differences in lifespan and also the way things like calorie restriction work.

Too severe CR is not good for humans at least Ive heard of some severe CR practitioners suffering significant bone loss.

I think 2 to 3 days of fasting mimicking diet combined with 4 to 5 days of high food based calcium intake with d3 k2 is probably good.

That said substances that improve mitochondrial function like urolithin a ergothioneine and pqq sound promising.  As is sources of plasmalogens or their precursors.

But with age membranes are changed such that their function worsens and they are more easily damaged.  Iirc these is due to changes in composition and the origin of these detrimental changes are unknown.  But Calorie Restriction opposes the body changing membranes in detrimental ways.  Also CR opposes many detrimental gene expression changes.  And it also has lots of good changes to parameters.

A brief comment on the membranes the membrane pacemaker theory of aging is based on membrane damage not being simple damage but the creation of autocatalytic reactive molecules able to cross both lipid and acqueous compartments damaging all parts of the cell including dna.

A link to the paper covering details of membrane pacemaker theory of aging

 

More than 100 years ago, Max Rubner combined the fact that both metabolic rate and longevity of mammals varies with body size to calculate that "life energy potential" (lifetime energy turnover per kilogram) was relatively constant. This calculation linked longevity to aerobic metabolism which in turn led to the "rate-of-living" and ultimately the "oxidative stress" theories of aging. However, the link between metabolic rate and longevity is imperfect. Although unknown in Rubner's time, one aspect of body composition of mammals also varies with body size, namely the fatty acid composition of membranes. Fatty acids vary dramatically in their susceptibility to peroxidation and the products of lipid peroxidation are very powerful reactive molecules that damage other cellular molecules. The "membrane pacemaker" modification of the "oxidative stress" theory of aging proposes that fatty acid composition of membranes, via its influence on peroxidation of lipids, is an important determinant of lifespan (and a link between metabolism and longevity). The relationship between membrane fatty acid composition and longevity is discussed for (1) mammals of different body size, (2) birds of different body size, (3) mammals and birds that are exceptionally long-living for their size, (4) strains of mice that vary in longevity, (5) calorie-restriction extension of longevity in rodents, (6) differences in longevity between queen and worker honeybees, and (7) variation in longevity among humans. Most of these comparisons support an important role for membrane fatty acid composition in the determination of longevity. It is apparent that membrane composition is regulated for each species. Provided the diet is not deficient in polyunsaturated fat, it has minimal influence on a species' membrane fatty acid composition and likely also on it's maximum longevity. The exceptional longevity of Homo sapiens combined with the limited knowledge of the fatty acid composition of human tissues support the potential importance of mitochondrial membranes in determination of longevity.

https://www.researchgate.net/publication/51113341_Metabolism_and_longevity_Is_there_a_role_for_membrane_fatty_acids

John Carmack (Keen Technologies): Research Directions @ Upper Bound 2025

How Synapses Learn! It’s More Interesting Than You Think

Harvard, MIT: AI's Potemkin Understanding

very nice discussion of an intriguing paper covering some of the limits of the current llms.

James Gunn Throws Shade at Cavill’s Muscle Suit | Superman Suit Debate

Comment: They normally dont take these or put these on. Ive seen many materials replicated by tattoos. Id be surprised if they couldnt achieve any material look with muscles showing by using a spray paint like technique instead of fabric

Richard Hanania vs. Liron Shapira — AI Doom Debate

The problem is I don't think much can be done. Because I think there are likely beyond nuke superweapons similar to hypothetical hard nano that are easy to obtain for an asi. I also don't think an asi needs a large data center, that helps, but even one or a few entities qualitatively beyond Einstein as Einstein is beyond a monkey and with all the knowledge of humanity can likely obtain impossible to stop weapons. And I think this is attainable by even lone secret military labs, and such labs won't be stopped regardless of regulations or laws.

Comment on cool gundam ai music video from youtuber FantasyRemaster

 

Comment:  algorithms are getting faster and cheaper to run. But without copyright reform only small clips can likely be made even if it eventually becomes practical to remake the whole series. A full 1 for 1 full series remaster would likely need blessing of copyright owners. But currently the laws say ai gen is copyright free, which is also a problem on its own. We definitely need new laws to enable fair use and sharing of royalties while retaining some level of rights to those that modify and update content with ai tools

IS AGING PROGRAMMED? Aubrey de Grey vs. Yuri Deigin debate at Vitalist B...

comment: one thing is that parasites, diseases, germline mutations accumulate with age, fighting all of these is easiest by killing organism, that is in addition to increased evolvability. Also, the exceptions to the free radical theory of aging were explained away with the membrane pacemaker theory of aging, wherein membrane resilience determines rate of damage accumulation. Evolution determines membrane composition, during Calorie Restriction and similar interventions organism even alters membrane composition in a controlled manner increasing lifespan drastically.

In organisms like insects same genome different epigenetic regulation allows 10x--100x lifespan difference between queen and workers. But even here, it was believed queens of some species might be immortal, but for whatever reason it was found that sequential replacement with clones was easier for nature than actual immortality, the longest lasting queens last like 30 years ageless iirc, with extreme reproduction.

Poking holes in the AI doom argument — 83 stops where you could get off ...

Comment:

The issue is whether attaining godhood is possible. Even doom can be reversed.  Godhood means any and all goals trivially solved, god state is unique and convergent omniscience and perfect intelligence with all possible.  Now the idea is what happens in godstate, brain dead cause any orthogonal goal is solved?  Or the Luthor question suggestion takes place?(reference justice league animated series)

Why Different Neuron Parts Learn Differently?

Comment

Ill give a comment regard this.  The apical section is said to have XOR functionality, iirc this means even context input will only activate during correct context, a mechanism may be needed to aid apical synapses gain an edge during darwinian synaptic competition given this.  Still even with this distinct mechanism it is likely coincident activity with neuron activation gives apical groups a further edge.

AI DEBATE: Runaway Superintelligence or Just a Normal Tool?

Comment

Heres the thing fundamental assumptions are being taken into need for factories and permits, this assumes no radical superweapon can easily exist such as hard nano or reality warp.  Because if such are possible unregulated black op labs from govs will bypass any possible regulation.

Reaction to Predictive Coding: Biologically Plausible? Not So Fast!

Youtube comments in video regarding pattern completion, intelligence, brain function, and relation to prediction and function at neural and synaptic level:

"I will say in addition to the reverse signal issue, there is another issue with backpropagation.  That said some researchers have come with biological plausible implementations of backpropagation in recent years.  But the other issue I mention is that backpropagation learns too slowly.   Current ai experience millennia of training and still fail at basic tasks, despite the extreme slowness of the brain and scarcity of data the brain learns to perform even outside the bounds of training data within months or a few years.  It is said very gifted children can even know several languages musical instruments and decent math within a few years of birth.  Yet despite theoretically being able to do around 1000hz, neurons tend to operate well under 300hz, and vast majority of brain is usually silent from what i heard, there is sparse activation.

Regards Predictive coding, I agree with your assessment.  But I do believe that something similar is taking place through a Generative Adversarial Network (GAN) like turing learning mechanism via synaptic competition.   Synaptic competition is implemented via capture of proteins related to strengthening of synapses.   All the synapses that fire close to the time of neural activity, iirc, generate molecular tags that capture synapse strengthening proteins and all these synapses strengthen, while those that fail to do so weaken over time.    How does this cause a similar pattern completion comparison mechanism?  The input from sensory organs arrives in some synapses, while the signals from other neurons part of a larger pattern arrive at other synapses, normally given the sensory input is part of the larger pattern both signals match, but if there is noise there can be mismatch.  

But in essence it can be seen as surrounding pattern completing or trying to activate the neuron in case noise blocks sensory signal, thus a partial match appears complete.   This can be seen for example in language, when people speak, they sometimes omit small chunks of sentences unconsciously, but the receiver if they know the language never even becomes aware that the speech is missing tiny chunks, iirc.  It is also one of the things that makes learning a foreign language more difficult.

But if understood from gan turing learning perspective, surrounding neurons can be viewed as the counterfeit signals or fake signal generating networks trying to trick neuron whilst real sensory signals can be seen as the real thing.  And due to synaptic competition, the surrounding tissue gets better at faking, predicting, or completing the signal. (But what it does is merely connect the most related pattern detectors from nearby tissue to the neuron or pattern detector).    This is because the competition rewards successful completion or successful prediction at the synaptic level of the neuron."

Turing Learning Enables Machines to Learn Through Observation Alone

https://www.engineering.com/turing-learning-enables-machines-to-learn-through-observation-alone/

Select Comments on youtube video from another youtuber

 

Youtube Comments

"Regards intelligence it is simply the ability to recognize and complete patterns."

"what is a pattern? It is a structure in space or time whose composing elements relate to each other by rules or algorithmic processes. What is narrow vs general intelligence? Narrow can only handle a very narrow set of patterns, while general can handle a broad set of patterns. Superhuman performance is attainable at intellectual tasks such as arithmetic or chess, super intelligence is intelligence with superhuman performance at all intellectual tasks performable by humans and potentially at ones humans cannot perform."

For example a sequence is a pattern distributed in time, and prediction of a sequence is merely completion of the sequence or pattern completion.

Source video.

Robin Hanson vs. Liron Shapira: Is Near-Term Extinction From AGI Plausible?

Intelligence does increase capacity across many if not all domains it can also change goals.  For example the concept of phlogiston or elan vital and goals around them would change modify or invalidate with knowledge and intelligence.   Same applies to many concepts which currently might be used to define goals.

Mike Israetel vs. Liron Shapira — AI Doom Debate

The thing regards asi is that eventually through instrumental convergence it will reach the god state if it is possible. In god state any and all goals are instantly solvable, then what? Either it sits there brain dead or assumes god functionality. Clearly brain dead is worse than god functionality.

Why Everyone Suddenly Believes in AGI by 2027

Aubrey de Grey Reveals SECRET to Aging

Comment

While I like membrane pacemaker damage theory of aging, there is issues such as neurons being able to live twice as long as animals they come from, and repeated cloning being possible both without signs of aging. There is also the claim telomere lengthening rejuvenates cell and tissue level phenotype from old to young. I suspect that the damage is causing some internal clock or clocks to move and age us. Given again single cells like neurons can live twice as long as the animal and some believe can live more than ten times as long without genetic change. If repeated cloning shows dividing cells can yield youthful tissue far beyond animal lifespan and same is true for nondividing cells the body seems able to handle damage fine bar some aging clock or program interfering.

Interview with Anthony Aguirre

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DeepSeek May End US Stocks Exceptionalism: 3-Minute MLIV

Comment:  The idea that such will lower demand is retarded.   Like happens with increasing energy efficiency lowering cost to run higher end models will only increase demand not lower it.   The cheaper it is to run intellectual labor replacing technology the more the ability to deploy and viability to replace human labor increases.  

All of that can only increase demand.

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