Wednesday, July 29, 2015

cool free program

Friday, July 24, 2015

Yet more evidence for programmed aging

Morimoto and Labbadia found the genetic switch occurs between two major tissues in an organism that determine the future of the species: the germline and the soma (the body tissues of the animal, such as muscle cells and neurons). Once the germline has completed its job and produced eggs and sperm -- necessary for the next generation of animals -- it sends a signal to cell tissues to turn off protective mechanisms, starting the decline of the adult animal...
"In a system where we can actually do the experiments, we discover a switch that is very precise for aging," he said. "All these stress pathways that insure robustness of tissue function are essential for life, so it was unexpected that a genetic switch is literally thrown eight hours into adulthood, leading to the simultaneous repression of the heat shock response and other cell stress responses."

The germline starts the slow suicide mechanism known as aging.