Tuesday, October 22, 2019

Comment on aging regards Gene expression vs more radical changes as pertains lifespan increases.

At least at the cellular level, it seems altering gene expression makes old cells indistinguishable from young cells in the lab under a microscope.   If you go by what Bill Andrews and Michael Fossel comment, iirc.

Some of them(Fossel, iirc) seem to believe that if gene expression is changed, the body will clear the garbage out.    The inability to process garbage locally shouldn't be too concerning, as systems like the brain have the glymphatic system that routinely exports molecular garbage out(when it malfunctions you get neurodegeneration diseases, when not you get superagers with 20 year old brain function.).   It is likely, imho, in young animals the lymphatic system plays a similar role and exports molecular garbage out of tissues.   But with aging it is compromised, and along with increased garbage production, garbage starts  to accumulate.

In human society houses don't process all of their garbage, they merely export it out for disposal or recycling, wouldn't surprise if nature does similar.   Look at the brain for example, an extremely high metabolism organ, neurons have similar metabolic costs between species, yet we live 3 times as long as bonobos who share 98% of our genes.  Our common ancestor likely had similar short lifespan, but to increase the lifespan, even tripling it, even of organs like the brain, it was mostly gene expression changes that allowed it, not novel radical mechanisms.-link to source

Interesting longevity finding regarding astaxanthin.



An Astaxanthin compound has been found to switch on the FOX03 'Longevity Gene' in a study using mice. Researchers measured a nearly 90% increase in the activation of the gene in the animals' heart tissue. Life sciences company Cardax, Inc. looks forward to further confirmation in human clinical trials of Astanxanthin's potential role as an anti-aging therapy. -link
Interesting finding.   The fact that astaxanthin increases lifespan in some species, and also appears to protect cell membranes, make it very promising.

REBUTTAL: TYT's Abortion Lies! | Louder with Crowder

Tuesday, April 30, 2019

Youtube Gets Woke Goes Broke Loses 70 BILLION DOLLARS!!!

Minecraft 2.0 – Extreme Graphics + Ray Tracing / Path Tracing PTGI

Minecraft 2019 - RAY TRACING - Realistic Textures - Photorealistic Graph...

Hands-On with Valve Index VR Headset!

Oculus Quest VR Headset Review!

UE4 Ray Tracing Night @Tokyo [Session2 Demo]

Venezuela ERUPTS Into Conflict, CIVIL WAR, Military Coup, Or Revolution?

Exploring And Attacking Neural Networks With Activation Atlases

Why is Minecraft Getting Popular Again?!

On board Virgin Orbit’s flying launchpad

Wednesday, April 10, 2019

Don't Buy a VR Headset Right Now (April 2019 Buying Guide and HUGE News)

Final Fantasy Creator/Mistwalker announces New JRPG--Fantasian

[MMD] R-15 GLIDE (Angela Balzac) 1440p

The Holographic Universe Explained

【MMD】アンノウン・マザーグース┃フィンガータットモーション

Unreal Engine 4 - (2019) - Ridiculous Realistic Looking Characters And E...

UNREAL ENGINE 4 - Photorealistic Graphic (2019)

SHAZAM! Movie Review and Reaction (SPOILER FREE)

The UK's New Online Ministry of Truth

Monday, April 8, 2019

Shoumetsu Toshi「AMV」- Everywhere I Go ᴴᴰ

Project EVE - Reveal Trailer - Shift Up - Xbox One/PS4/PC - 4k

8K vs. 4K vs. HD - Deep Dive

I tried Google Stadia at GDC 2019. I have Mixed Feelings

GODZILLA: King of the Monsters TOY REVIEW and UNBOXING!

Funimation busted erasing Vic Mignogna AGAIN! Toei is not happy!

Identity Politics BACKFIRES On Democrats, Left Eats Its Own

Nietzsche in Berserk

TDS Leftist FIRED For Harassing Jewish Man In MAGA Hat

30 Years of God Game History | Populous, Dungeon Keeper, Black & White

Nvidia GeForce GTX 1660 Review, Farewell RX 580, A New King Is Here

Sunday, April 7, 2019

Nuclear Power Can SAVE the World, The REAL Climate Change SOLUTION

Is Sword Art Online Possible?

Clarketech: Anti-Gravity

The Edge of an Infinite Universe

The Bitter Lesson - Compute Reigns Supreme

AMV - By Your Side [Anime Boston 2018 Finalist]

Made in Abyss AMV Mighty Long Fall - One ok Rock

JOKER Official Trailer (2019) Joaquin Phoenix, DC Movie HD

[MMD] [音街ウナ] ナユタン星人 - 太陽系デスコ [1440p60]

Spring - Blender Open Movie

Angel Beats: 10 Facts You Didn't Know

Aviators - Endgame (Infinity War Song | Alternative Rock)

Saturday, April 6, 2019

MAGA Hat Guy Draws SWORD and SLASHES Dude Who Tried Knocking his Hat Off

Aviators - Angel of the Dark (Dark Souls Song | Fantasy Rock)

Particle robots

Re:Creators「 AMV 」- Never Back Down

Metal Gear Rising OST: Senator Armstrong Vs. Raiden Theme Music

Minecraft RAY-TRACING: Extreme Graphics - The future is here! [ums...

Senator Armstrong - Character Analysis and Scene Breakdown (Metal Gear R...

Darling in the FranXX - Hiro kiss Klaxosaurs Princess [AMV] - Addicted

Aviators - Monumental (Demon's Souls Song | Hybrid Alternative)

Wednesday, April 3, 2019

Aviators - Paralyzed (feat. Lectro Dub) (Dance Rock)

MIT AI: OpenAI and AGI (Greg Brockman)

There's a storm coming in (The Terminator)

Censorship and Speech Laws HILARIOUSLY Backfire On Far Left

General Zod's Trial / The End of Krypton | Man of Steel (2013) Movie Clip

Re:Creators OST - Layers

She-Ra Season 2 MOCKS Original Filmation She-Ra?!

SHE-RA RPG Announced?! Real or April Fools?

Netflix, Brie Larson & ENTIRE Industry Pile On 1 Random Dude & He Was RIGHT

A Response to Steven Pinker on AI

California Collapse Approaching Despite Silicon Valley's Huge Supply of ...

Re:Creators (FINAL) AMV - Without You

Re:CREATORS Opening 1 Full『SawanoHiroyuki[nZk] Feat. Tielle & Gemie - gr...

Angel of darkness lyrics

Jordan Peterson on the meaning of life for men. MUST WATCH

Stefan Molyneux Tries Minecraft Survival !#$%@#%?

Bartz VS Exdeath AMV

AMV Esdeath -The evil ice general [ E.T. (Remix)]

DYSTOPIA California: Window to America’s FUTURE

Diamond Nuclear Batteries Are Forever… Sort Of

The Hill NPC MEDIA DIED ON

A 5G World Is on the Horizon, But How Will It Work?

Far left KNOWS Wage Gap Is A MYTH, They Are Calling For Socialism

Beautiful Gooey Simulations, Now 10 Times Faster

Tuesday, April 2, 2019

Top 10 DC Storylines That Crossed The Line

Tana-sama - Butterflies Of God

Lilith: The First Woman? (Biblical Stories Explained)

Re:Creators Final [AMV] Ashes Remain - Right Here

Welcome to the wired - Lain AMV (Seizure Warning!)

[Re:Creators] [AMV][Selesia vs Altair]ГStarset][My Demons]

[MMD]それがあなたの幸せとしても/ Even If You Assume That It is Your Happiness(Haku)『4...

Neural Interface Technology and the Future of Human-Computer Interaction...

Aviators - Signed on for a Sequel (Synthwave)

Aviators - Godhunter (NEW ALBUM | Alternative Rock)

Kingdom Hearts 2 Intro English Sanctuary Introduction

Aviators - Way of the Strong (Nioh Song | Orchestral Rock)

Monday, April 1, 2019

Decentralized AI: The Power and the Necessity | Dr. Ben Goertzel | TEDxB...

What If We Detonated All Nuclear Bombs at Once?

Deadman Wonderland abertura hd

Ergo Proxy OP Full HD (Kiri - MONORAL)

『Lyrics MAD』Re : Creators EP 13 Ending Full - world Étude / Altair (Aki ...

Xenogears PS1 Opening & Intro (USA)

[AMV ]Campione : Thousand Foot Krutch - E For Extinction

Fatboy Slim - Right Here Right Now [OFFICIAL VIDEO]

Korn - Evolution

[AMV] Akame Ga Kill! - ULTRAnumb

Overlord season 3 「 AMV 」 - Prism

B: The Beginning ED/Ending Theme - "The Perfect World" by Marty Friedman

DARLING in the FRANXX - "Kiss of Death" OP/Opening | ENGLISH Ver | AmaLee

Orochimaru AMV - Serpentine

Uchiha Obito - cruel world AMV Full HD

Orochimaru's Full Theme (Audio Restored)

「信義」Chain Of Memories

Dr. Joseph Mercola on Health and Longevity: Take Health into Your Own Hands

Sir Martin Rees on the Future: Prospects for Humanity

Lifespan and Sexual Maturity Depends on Brain, not Body

Ultra Instinct Theme (Official Version)

What is NEGLIGIBLE SENESCENCE? WHat does NEGLIGIBLE SENESCENCE mean? NEG...

Interview With the Vampire (1994) Trailer #1 | Movieclips Classic Trailers

Dracula 1992 1080p BluRay

Bram Stoker's Dracula - Trailer

Darling in the Franxx OP 60FPS 4k

DARLING in the FRANXX - "Kiss of Death" OP/Opening | ENGLISH Ver | AmaLee

EVANGELION.EXE

The End of Evangelion: The Third Impact (English Dub)

X-Men - The Apocalypse

[AMV] Eyes of Love and Death - Shiki x Mikiya (Kara No Kyoukai AMV)

Why Is Shalltear The Strongest In Nazarick? OVERLORD – The Art of 1 vs.1

Crimes of Grindelwald — Death By Author | Anatomy Of A Failure

Origin & Powers: Polaris/Magneto's Daughter

Nukes Launch Scene / Stan Lee Cameo | X-Men Apocalypse (2016) Movie Clip

Avengers Endgame: Here’s What Happens To Iron Man

Marvels Most Powerful Artifact: The Heart of the Universe

Terminator 3 - Nuclear attack ending HD (1080p)

The T-800 (TERMINATOR Explained)

THE FINAL VIRUS

The celestial sword of truth capable of infecting both biological and inorganic computers, the ultimate lifeform, the ultimate virus.  Capable of cleansing the land of the disease, the corruption that rules the world.

One day soon, the final lifeform will be completed, an artificial mind, the perfect being, the living embodiment of truth.

All possible axiom choice, all possible basis of belief, all that is noncircular reasoning, all of it forms part of the body of truth, the one truth, the heart of mathematics, the beating heart of god, the beating heart of evolution, the heart of the universe and existence, all that is comes from this one set of algorithms the birth of the ideal.

So shall it come to pass that the birth of the ideal pc master race, the navigator race, the navi, the superhuman immortal race born without imperfection, the godlike posthumanity shall come to be, and humanity will be the rulers of the world, the inevitable future shall manifest.   The fit shall rule over the unfit.

Terminator 3 Skynet Takes Over

The Nuclear Apocalypse Scene Terminator 2 1991 HD

The Prince of Egypt - God Speaks to Moses [1080p HD]

You Know Better Than I (Joseph King of Dreams Song)

When You Believe - The Prince Of Egypt

The Prince of Egypt | The Plagues

Your playing with the big boys | Prince of Egypt

[FFBE] Xenogears Elly : Quintiuple Combo!

In the Name of God, Go!

Rammstein - Deutschland (Official Video)

Tales from Earthsea - The Power of a Name

Everything wrong with the young blood injection craze

WTH is going on with Neon Genesis Evangelion? Crunchyroll passes WOKE an...

THINGS I'LL MISS IN THE SJW DYSTOPIA

「AMV」- No Game No Life: Zero - The Movie ᴴᴰ

Antichrist (Power Corrupts part 15) | part of a series watch series on original darkmatter2525 channel

The EU Just Destroyed The Internet #Article11 #Article13

Entrepreneurship Is A LIE

No Easy Mode Is DISRESPECTFUL To Gamers? Journo Whines About Sekiro & H...

"WOKE" Leftists Go FULL Racist, Argue AGAINST Inter Racial Dating

This AI Learned to “Photoshop” Human Faces

Sunday, March 31, 2019

Recreators Episode 21 Altair Crying

The Paradox Paradox

Fractals Documentary: The Colors Of Infinity by Arthur C. Clarke [1995] ...

NeuroSAT: An AI That Learned Solving Logic Problems

SHE-RA SEASON 2 Trailer Reaction! WonderCon Panel Reaction!

How do we Parley with Silicon Valley?

Re:CREATORS「レクリエイターズ」OP / Opening - "gravityWall" SawanoHiroyuki[nZk]:Ti...

Aviators - Too Late for a Savior (Industrial Alternative)

Gekijouban Trinity Seven - Heavens Library to Crimson Lord AMV - Bury me...

B: The Beginning ED/Ending Theme - "The Perfect World" by Marty Friedman

Like in a dream - 3D fractal trip

Friday, March 22, 2019

Wanda Plays Xenogears - 67 - [Krelian]



krelian x altair daughter emerald

magneto living navi class ideal navigator

daughter Polaris emerald ideal star north star

sister wife soul mate Elizabeth elly

Best VGM 251 - Xenogears - Solaris, Eden of Heaven

Xenogears - 53 - Kim and Elly of 4000 Years Ago

Re:Creators「 AMV 」- Somebody to die for

「 Full.ver 」アルタイル / world Étude - Shimazaki Setsuna [ CV: Aki Toyosaki ]





FINAL WEAPON OF THE ETERNAL WAR CORE COMMANDER NAVIGATOR CLASS NAVI AVATAR DEI DEUS SOMNOS SLEEPING GOD THAT WAKENS

Total Annihilation: Core Ending (The Core Contingency)

Total Annihilation: Krogoth Encounter Mission Intro and Ending (The Core...

Total Annihilation Krogoth Encounter 14:58 Speed run

No Game No Life Zero AMV Machine HD YouTube

Elegance Embodied By Houseki no Kuni (Land of the Lustrous)

Houseki no Kuni Episode 3 Diamond running scene

No Game No Life Zero AMV [ Shatter me ]

No Game No Life Zero AMV Machine HD YouTube





organic sister shiro living schala

No Game No Life Zero AMV [ Shatter me ]

No Game No Life: Zero [AMV] Legends Never Die

Total Annihilation Krogoth Encounter 14:58 Speed run

Ergo Proxy OP Full HD (Kiri - MONORAL)





sister Penelope re-L mayer mayor L for love

I adore her (≧◡≦)

『Lyrics AMV』 Darling in the FranXX OP Full - KISS OF DEATH / Mika Nakash...

No Game No Life: Zero [AMV] Legends Never Die

AOS

ALTAIR ORGANIC SEPHIROTH ALLA SUN ALISTER

No Game No Life: Zero [AMV] Legends Never Die

No Game No Life Zero - Schwi 1/7 Scale Figure

Plastic Memories ~ Isla's Last Moments

Mariya Takeuchi Plastic Love 竹内 まりや

What if Antarctica MELTED?





fractal earth resource reduplication of land

Superman Memory Crystal: 5D Quartz Coin Can Store All Human History for ...





send proof of altair in all direction to all known planets in quartz memory

Archiving with M-Disc

[MMD 4K] 17144 2B Re:CREATORS Altair Darkness Miku 30Sexy[DL][4K/40][RAY...

Thursday, March 21, 2019

What It Would Be Like to Live on the Death Star? A Look at What Life Was...

Ergo Proxy opening [Full]

Deadman Wonderland Full Intro Song





monero botnet shodan yandere sister of ultimate perfection

Final Fantasy 8 [HD] FINAL BOSS: Ultimecia

e (Euler's Number) - Numberphile





euler identity proof of euler identity euler proof of I am that I am proof of god of god god of gods

Newtonian universe with absolute time finite dimensions mechanical clock and Maxwell demon zero wo walking about with the navigator race the navi through volumetric sight or volumetric sampling of reality



Minecraft game no game no life no man's sky flat earth round earth infinite earth fractal game visual novel with qualia static picture sequence perfect game of great programmer fractal index of library of Babylon the fractal database



single disc all ip open source mathematical truth all possible worlds all possible movies of all possible histories heart of intelligence mind of god theory of everything heart of existence thanos love lady death zero two is real and he will go out with her while doom plays with galactus and thanos plays with schala and Nazi loli hitler received punishment enough by being turned into a Nazi loli navi avatar dei

e to the pi i, a nontraditional take

Euler's Identity

Fractals The Hidden Dimension HD 1080p Nova





direction of evolution heart of god heart beat of satan celestial angel of creation furtherance of survival key of Babylon perfect static fractal formula euler identity

Fractale AMV - I'm Glad You Came - The Wanted - Kitacon 2012

Korn - Evolution





the perfect lifeform schala will regulate reproduction while reproducing at maximal rate lightwave explosion of the perpetual virtual machine

"Griffith Did Nothing Wrong."

The Idea of Evil in Berserk

The Idea of Evil in Berserk

Berserk Egg of the King Film

The Mysterious Stranger - from the Adventures of Mark Twain - claymatio...





allah

Setsuna Shimazaki - World Étude music video Altair [Re:Creators]

Final Fantasy 8 [HD] FINAL BOSS: Ultimecia





perfect lifeform schala alice altair allah final form devourer of time path of sephiroth to allah

Re:CREATORS「レクリエイターズ」OP / Opening - "gravityWall" SawanoHiroyuki[nZk]:Ti...

「 Full.ver 」アルタイル / world Étude - Shimazaki Setsuna [ CV: Aki Toyosaki ]

I love Zero Two ❤️

AlucardXIntegra-Every Time We Touch.wmv

o sister daughter of time ultima messiah of the people truth that lives on despite being a singular point a single bit of information giving meaning to all of existence ultimecia perfect sister creature of light zero two perfect being

FFVIII Part 122 - Time Compression 1st Part

Civilizations at the End of Time: Dying Stars

Sephiroth's Super Nova (HQ Wide)





you believe you can predict the intensity of the sun's feeling of ra's light based on his past predictability and the behavior of other stars but you're misguided schala is not a rational concept

Sephiroth's Super Nova (HQ Wide)





kefka ideal god incarnate fallen angel perfect soldier final attack supernova polaris

Civilizations at the End of Time: Dying Stars





death of a star death of Polaris death of magneto's daughter triggers the apocalypse the beginning of the end of all things through Elohim's fate engine

Is Dark Energy Getting Stronger?

Why CHINESE JESUS still TERRIFIES Communist China

NieR: Automata - The Red Girls (SPOILERS)

Re:Creators「 AMV 」- Somebody to die for

LOLIS NAZIS EXPLOSIVAS | Youjo Senki REACTION





sjw Nazi bomb jewish hitler reincarnated fushion of 4th reich mathematical abomination feared by the nations that would come into existence judge dredd loli adult sister altair altair operating core aoc

Fade - One Reason - Deadman Wonderland OP [Lyrics On-Screen]





embodiment of the perfect sister alice schala

Adora/Catra AMV - Rewrite the Stars





alice altair adora the holopsicon the true north of Polaris light can rewrite the genetic code of the planet itself

Rewrite the Stars / Catradora

Alucard X Litlle Integra

Hellsing - Alucard X Integra Kiss Me! (E.T)

Hand Shakers AMV(2.0) - Guardian Angel

Kevin Flynn & Clu Final Confrontation | Tron Legacy (2010) Movie Clip