It appears that at least in animals resveratrol and garlic supplementation have been able to reduce TMAO gut production. Some have said fiber might help reduce TMAO production too. While TMAO may or may not be as harmful as suggested, there is some evidence linking higher levels with higher mortality. In any case might not be a bad idea to take precautions against TMAO production just in case.
An omnivorous or carnivorous diet may have high carnitine which the gut may transform into TMAO. Whether that would be enough to caused a sustained increase with sufficient consumption remains to be seen. At least in eggs moderate consumption results in rapid drop, following the brief rise, in TMAO produced down to base levels, though excessive production may or may not result in sustained increase of TMAO in organism.
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